Regulating swelling in lab-grown kidneys using electricity, Isaac Breinyn, GS and Gawoon Shim, GS (2267847)

Pumping in organs is an essential and ubiquitous step across the developmental processes in organs such as alveoli, kidney ducts, and the gut. Once a hollow structure is established, it undergoes cycles of swelling and relaxation that precede multiple critical developmental events such as branching. Here, we show that electrical cues can drive the swelling of kidney organoids. Interestingly, the level of swelling varies directly with the strength of the electric field, allowing us to program both the rate of growth and the overall size of the organs.

Isaac Breinyn, GS: https://www.linkedin.com/in/isaac-breinyn-7b46a1143/ + https://isaacbreinyn.wordpress.com/