Search for tag: "biological engineering"
3D Printing of Complex Materials for Biomedical and General Use, Lauren Ava Rawson, UG '23 (2270891)Cell-cell connections are far stronger than cell-substrate connections. The proteins that cells use to connect to non-cellular material are weaker than the proteins used in cell-cell connections. On…
From Research Princeton Research Day
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Connections between Graph Theory and Single-Chain Nanoparticle Morphologies, Sophia Colmenares, UG '24 (2277355)Single-chain nanoparticles are intriguing materials inspired by proteins that consist of a single precursor polymer chain that has collapsed into a stable structure. In many prospective applications,…
From Research Princeton Research Day
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Uncovering the Architecture of a Photosynthetic Turbocharger Through Super-Resolution Microscopy, Angelo Kayser-Browne, (2262922)Plants use a protein called Rubisco to convert carbon dioxide into organic compounds, allowing them to “make” their own food through photosynthesis. A type of green algae called…
From Research Princeton Research Day
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Is Telomerase The Kryptonite of Human Cytomegalovirus?, Chloe Cavanaugh, GS (2264575)Human Cytomegalovirus (HCMV) remains highly prevalent and can cause severe disease in immunocompromised hosts. Congenital infection is a leading cause of congenital neurologic defects. There is no…
From Research Princeton Research Day
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Improving CAR T Cell Immunotherapy Response to Diffuse Large B Cell Lymphomas: A Characterization of Metabolic Heterogeneity Across Tumor Models, Tristan Szapary, UG '24 (2278893)Diffuse Large B Cell Lymphoma (DLBCL) is a prevalent form of blood cancer, with a devasting survival rate of three years. Current treatments begin with aggressive chemotherapy, yet a percentage of…
From Research Princeton Research Day
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Pitch Tunneling in Baseball, Ben Zenker, UG '24 (2264109)Pitch tunneling in baseball is when two pitches look the same for most of their trajectory towards home plate, but then move in opposite directions. Pitchers utilize pitch tunneling to try and fool…
From Research Princeton Research Day
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The Sub-Two Hour Marathon: Applying an Engineering Lens to Understand How Eliud Kipchoge Did the Impossible, Lola Wheeler, UG '23 (2833924)This research project successfully provided insight into what it took to break, what is often referred to as, the “impossible barrier” – finishing a marathon in under 2 hours. In…
From Research Princeton Research Day
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iGEM: Interkingdom Communication, Fatima Sarfraz, UG '26; Ja'nae Gordon, UG '26; Dania Khalid, UG '26; Parth Rana, UG '26; Fatima Sarfraz, UG '26; Sanjana Venkatesh, UG '26; Brian Park, UG '26; Maia Weatherly, UG '25; and Meryl Liu, UG '25 (3993888)The Princeton iGEM team will be undertaking a project to rewire bacterial and mammalian cells to communicate with each other via protein secretion. Bacterial cells can secrete proteins that can enter…
From Research Princeton Research Day
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E-cadherin: Biological Glue to Improve Cell-Material Adhesion, Youn Kyoung (Elena) Cho, GS (2279756)Biomedical devices that penetrate the skin, such as implants and vascular access devices, rely on a stable attachment between the tissue and material to prevent complications. If the adhesion fails…
From Research Princeton Research Day
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What Seems to be the Problem? Stigmatizing Language in Patient Medical Notes, Abinitha Gourabathina, UG '23 (2262024)Stigmatizing language in medical notes can prevent a patient from acquiring proper treatment. Reading medical notes containing biased language can influence subsequent clinicians’ perception of…
From Research Princeton Research Day
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Exploring the Prospects and Challenges of a Novel n-Doped Organic Semiconductor, Colin Brown, UG '24 (2264872)The use of organic semiconductors (OSCs), i.e, conductive polymers, has risen greatly over the last few decades, as scientists have taken advantage of their unique properties, including greater…
From Research Princeton Research Day
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Chemical Tools to Understand Protein Interactions, Zoe Merz, GS (4088732)The proteins in our cells are not solo players; they constantly engage and cooperate with other proteins. These interactions are very important for the normal function of the cell and are relevant to…
From Research Princeton Research Day
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Ripples in my protein: How different parts of a protein talk to each other and change its structure, Sohit Miglani, GS (4088652)Proteins change their structure to perform different functions. We have always known that proteins can exist in different structures but the molecular mechanisms that allow parts of a protein to talk…
From Research Princeton Research Day
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Going Ballistic! Elucidating the Transition from Repetitive Head Injuries to Chronic Traumatic Encephalopathy Using a Novel Ballistic Impactor in Flies, Nicole J. Katchur, GS (2272683)Chronic traumatic encephalopathy (CTE) is a disease that affects the brain and worsens over time. CTE is associated with repetitive brain injuries (rTBI) and may lead to symptoms like memory loss and…
From Research Princeton Research Day
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Considering Intergenerational Equity: The Ethics of Deploying a Mosquito Gene Drive in Sub-Saharan Africa, Felicia Sanders, UG '25 (2770420)Malaria was eradicated in the United States in 1951, but it is now the sixth biggest cause of death in low-income nations, and conventional preventative approaches, like pesticides, are becoming…
From Research Princeton Research Day
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Regulating swelling in lab-grown kidneys using electricity, Isaac Breinyn, GS and Gawoon Shim, GS (2267847)Pumping in organs is an essential and ubiquitous step across the developmental processes in organs such as alveoli, kidney ducts, and the gut. Once a hollow structure is established, it undergoes…
From Research Princeton Research Day
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