Search for tag: "cell"

A Comparative Analysis of Nuclei Enrichment Protocols for Single-Cell Sequencing Advised by: Fenna Krienen - Princeton Neuroscientist Institute

An Analysis of Phase Separation in Short Chain Homopolymer Systems Advised by:William Jacobs - Department of Chemistry Fan Chen

Investigations of Biophysical and Biochemical Mechanisms of Proteins Involved in T. gondii Parasite Propagation Advised by:John Jimah, Molecular Biology Erik Zupa, Molecular Biology

Following fusion of the egg and sperm during fertilization, the embryo divides to form a structure called a blastocyst. Differences between cells in the embryo emerge by the formation of the early…

Our lungs are beautifully designed and energetically efficient gas-exchange systems that are formed by complex, tree-like networks. However, sometimes lungs do not form correctly during embryonic…

Proteins, a fundamental component of all cellular processes, exhibit diverse functions which are dictated by their unique structures. Large language models (LLMs), such as ESM1-b, have recently…

Biomanufacturing is the use of cell machinery to produce high-value chemicals. Although a growing field, used in the production of everyday products such as insulin and Vitamin C, the current…

This summer, the Princeton iGEM team will be undertaking a synthetic biology project to compete in the iGEM competition this coming fall semester. My proposed project embarks on the global issue of…

Inflammatory bowel disease (IBD) presents a significant healthcare challenge, affecting millions worldwide with its chronic inflammation of the gastrointestinal tract. Current treatments, mainly…

Vascular malformations are the result of atypical development of blood vessels. As with many rare conditions, vascular malformations are understudied, and the mechanisms underlying their formation…

The motivation of our project is to create a treatment that would isolate and attack cancer cells rather than both cancerous and non-cancerous cells. The impact of this would be profound, as patients…

From wound healing to cancer metastasis, collective cell migration is a key step to these biological processes. However, many of these migrations are localized and does not impact the whole system.…

Toxoplasmosis and malaria are parasitic diseases with significant global health impacts. An estimated 1 in every 3 individuals worldwide are infected with toxoplasmosis, and over 600,000 die annually…

Influenza A virus (IAV) creates a significant burden of disease in the human population every year, including millions of cases of severe illness, and hundreds of thousands of deaths. Like all…