Search for tag: "molecules"

The Princeton iGEM team will be undertaking a project to rewire bacterial and mammalian cells to communicate with each other via protein secretion. Bacterial cells can secrete proteins that can enter…

Cannabidiol (CBD) has been gaining popularity as a therapeutic, targeting diseases such as epilepsy and Alzheimer’s. Like many other small molecule drugs, CBD has low solubility and…

Trillions of bacteria live in our intestines. This community of microbes is called the gut microbiota. The gut microbiota is a rich source of small molecules. While the majority of gut…

Communication is an incredibly powerful tool for species to survive in a hostile environment. With that in mind, it is perhaps unsurprising that even some of the simplest life forms, bacteria, have…

The Gitai lab has developed approaches that enable discovery of new drugs with novel mechanisms of action and are using these methods to discover new antibiotics that our society desperately…

Cryo-EM Studies of Organelle Formation in Parasites Mentors: Prof. John Jimah, Molecular Biology Nathan Fowler (Research Specialist), Molecular Biology

As a combination of rising sea levels, extreme weather, and groundwater overuse leads to increasing seawater encroachment in coastal areas, it’s essential that we learn more about the resulting…

The emergence of new diseases, the rise of drug resistance, and the continued prevalence of chronic conditions that remain difficult to treat, such as cancer and Alzheimer’s, create a growing…

Enzymes have been studied for centuries; however, our knowledge of them is constantly evolving. New enzymes are still being discovered, which opens the door for further studies of enzymatic…

This summer, I had the opportunity to work with the Princeton University Laser Sensing (PULSe) Lab, which is interested in laser-based spectroscopic systems. Their work has many real-world…

Per- and polyfluoroalkyl substances (PFAS) are a family of chemicals that are persistent and ubiquitous in the environment. While perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS)…

Many oral delivery drugs are in the amorphous state, stabilized by an amorphous polymer. Over time, these drugs tend to "flow," resulting in significant changes to the drug product that…

Trillions of bacteria live in our gut. This community of microbes is called the gut microbiome. The gut microbiome is a rich source of small molecules. While the majority of gut microbiome-derived…