Brian Chait, Rockefeller University - Butler Seminar Speaker 3-12-2021
From MOL MolBio Zoom Webinar March 25th, 2021
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"Addressing Challenging Problems in Proteomic Research”
Abstract: Although mass spectrometry-based proteomics is facilitating many new avenues of biological research, this remarkable set of tools is still limited in its applications. I will discuss some of these limitations and our efforts to address them. In particular, I will address methods for accurately modeling large macromolecular assemblies that may be flexible and undergo conformational changes; capturing specific interactions that are weak and/or transient; elucidating dynamic macromolecular processes, identifying large repertoires of tightly binding antibodies against targeted antigens, as well as addressing limitations in the signal-to-noise ratio and dynamic range of current mass spectrometric technologies.
- Tags
- Date
- March 10th, 2021
- Speaker
- Brian Chait - Rockefeller University
- Location
- Zoom
- Appears In